SOA Norms Report

  1. Introduction
  2. Collecting the Raw Data
    1. ARIC
    2. GMBI
    3. NACC
    4. MCSA
  3. Summarizing the Raw Data
    1. Demographics
    2. Instruments
  4. Generating the Normative Samples
    1. ARIC
    2. GMBI
    3. NACC
    4. MCSA
    5. Pooled
  5. Summarizing the Normative Data
    1. Demographics
    2. Instruments
    3. Groups by Instruments in the Pooled Sample
  6. Generating Instrument Level Models
    1. Notes on the Trail Making Tests
    2. A Note on the LDST
  7. Generating Domain Level Models
  8. Generating Algorithmic Classifications

Generating the Normative Samples

ARIC

Visit 5

The process for deriving the Normative Sample for ARIC Visit 5 is explained in detail on page 9 of the the ARIC Visit 6 Manual 17: ARIC Neurocognitive Exam Manual from April 2017.

Visit 6

For the Normative Sample at Visit 6, we enforced exclusion criteria similar to those enforced at Visit 5. Details follow.

  • Dementia Medications (Cholinomimetics) : We excluded participants taking cholinomimetics.
  • History of Neurological Diagnosis : We excluded participants with a histoy of Neurological Diagnosis.
  • Race : We excluded participants who were neither black nor white.
  • Cognitive Decline : We excluded participants who experienced cognitive decline between Visits 5 and 6.
  • Stroke : We excluded participants who had ever been hospitalized for Stroke.
  • Adjudicated Cognition Status : We excluded participants who did not receive a "Normal" Adjudicated Cognition Status at Visit 6.
  • Level 3 Dementia : We excluded participants with a Level 3 Dementia Status.
  • APOE : We excluded APOE44 participants.
  • Self-reported Memory : We excluded participants with a self-reported memory complaint.
Overall

Multiple Observations : If a participant had multiple observations, then only the earliest visit was used.